Industrial Bioengineering

Cerca

Pietro Renato Avallone

Pietro Renato Avallone, classe 1994, ha conseguito la laurea in Ingegneria Chimica nel 2018 presso l’Università degli Studi di Napoli Federico II con una tesi sul comportamento reologico degli additivi di cemento idrosolubili per la stampa 3D. Ha conseguito il dottorato di ricerca in collaborazione con la azienda Perfetti Van Melle nel 2022, con una tesi sulle proprietà reologiche di idrogeli di gelatina animale ed idrocolloidi vegetali.

Durante il dottorato, attraverso l’analisi delle proprietà di gelazione degli idrogeli, è stata individuata una stretta relazione tra la cinetica della gelazione e le proprietà meccaniche e morfologiche dei gel di gelatina.

Da Febbraio del 2022 ha lavorato presso l’Università del Sannio per un anno come postdoc ad un progetto sul comportamento reologico di sistemi complessi.

Come visiting researcher, ha recentemente trascorso alcuni mesi alla Delft University of Technology (TU Delft) nei Paesi Bassi con un progetto sulla dinamica delle bolle in media viscoelastici.

Durante la sua attività di ricerca, P.R. Avallone ha pubblicato nove articoli su riviste internazionali, focalizzando l’attenzione sulla reologia dei fluidi complessi, in particolare su soluzioni viscoelastiche, gel ed emulsioni.

I suoi interessi di ricerca includono il comportamento reologico di cinetiche di gelificazione, la microstruttura, la cristallizzazione di materiali complessi, le transizioni di fase assistite da ultrasuoni e la dinamica di bolle in mezzi viscoelastici.  

Attualmente è Ricercatore a Tempo Determinato (RTD-A) presso il Dipartimento di Ingegneria Chimica, Materiali e Produzione Industriale (DICMaPI), UNINA.

È titolare del corso di Transport Phenomena in Lining Systems per gli studenti di laurea magistrale in Industrial Bioengineering.

Paolo Bifulco

Paolo Bifulco è professore ordinario di Ingegneria Biomedica presso il Dipartimento di Ingegneria Elettrica e delle Tecnologie dell’Informazione. Ha conseguito la laurea in Ingegneria Elettronica presso l’Università Federico II di Napoli e il dottorato di ricerca in Bioingegneria. È stato Visitor Researcher presso l’Università di Southampton (UK). È stato associate editor e revisore per diverse riviste internazionali. Ha partecipato a numerosi progetti di ricerca nazionali e internazionali. Ha svolto attività didattica nel campo della bioingegneria tenendo, tra gli altri, corsi di Strumentazione biomedica e Ingegneria clinica. La sua attività scientifica si è sviluppata principalmente nel campo della strumentazione biomedica, dell’elaborazione e dell’analisi di segnali e immagini biomediche, della telemedicina e della telematica sanitaria.

David Cacchiarelli

Davide Cacchiarelli grew up in Rome where he carried out his undergraduate studies in Biotechnology and Biology. He obtained a Master Degree and a Doctorate Degree in Genetics and Molecular Biology from University of Rome “La Sapienza”, working on mechanisms of RNA regulation. In 2011 he moved to The Broad Institute of MIT and Harvard and The Department of Stem Cell and Regenerative Biology at Harvard University to focus his research on the rules governing cell fate transitions and reprogramming using genomic approaches.

He returned to Italy in 2017 thanks to the Armenise Harvard Foundation Career Development Award and now he leads a young research group focused on understanding the dynamics of cell fate decisions at TIGEM, the Telethon Institute of Genetics and Medicine in Naples.

Davide Cacchiarelli’s work aims to identify the mechanisms controlling cell fate decisions during cellular differentiation, conversion and reprogramming, and how such processed are affected by genetic mutations of key regulatory proteins including transcription factors. To achieve this goal he proposes to integrate descriptive, functional and single cell genomics to dissect how genetic elements and their variants impinge on the temporal and spatial control of gene expression.

Davide Cacchiarelli is leading the Laboratory of Integrative Genomics at TIGEM, bringing together an interdisciplinary approach engaging stem cell biology, cellular engineering, genomic approaches and mathematical modeling.

Marcella Cesana

…prossimamente…

David Dannhauser

Uno dei nostri risultati è stato lo sviluppo di un dispositivo di allineamento in tre dimensioni, a basso costo, per particelle e cellule basato sull’uso della microfluidica. Il dispositivo può essere facilmente accoppiato ad un’ampia selezione di sistemi per indagine ottica. Sulla base dell’allineamento cellulare indotto dalla viscoelasticità di un fluido polimerico, abbiamo sviluppato un sistema di diffusione della luce statica basato su una telecamera. Grazie a tale luce, è possibile ottenere la caratterizzazione individuale di cellule viventi o di marcatori di biomolecole in condizioni di flusso continuo. Pertanto, i profili di scattering ottenuti rivelano informazioni importanti sulle caratteristiche morfologiche delle particelle e cellule studiate, aiutando a distinguere diversi tipi cellulari o biomarcatori l’uno dall’altro o anche cellule fisiologiche da cellule patologiche. In effetti, una caratterizzazione unicellulare così semplice da usare può essere considerata, in prospettiva, come un metodo utile per una diagnostica rapida ed economica del sangue umano.

Fanny Ficuciello

Fanny Ficuciello received the Laurea degree magna cum laude in Mechanical Engineering and the Ph.D. degree in Computer and Automation Engineering both at University of Naples Federico II in 2007 and 2010 respectively.
From September 2009 to March 2010 she was a visiting scholar in the Control Engineering Group at University of Twente, The Netherlands.
Currently, she is Assistant Professor of Industrial Bioengineering at the University of Naples Federico II. Her research activities are focused on biomechanical design and bio-aware control strategies for anthropomorphic artificial hands, grasping and manipulation with hand/arm and dual arm robotic systems, human-robot interaction control, variable impedance control and redundancy resolution strategies. Recently, she is involved on surgical robotics research projects, as a member of the ICAROS center (Interdepartmental Center for Advances in Robotic Surgery) of University of Naples Federico II.
She has published more than 60 journal and conference papers and book chapters. She is Editor of the volume “Human Friendly Robotics, 10th International Workshop” within the Springer Proceedings in Advanced Robotics. She is the recipient of a National Grant within the “Programma STAR Linea 1” under which she is the PI of the MUSHA project. She is responsible of the research objective “MRI-TRUS fusion algorithms and control strategies for robot-assisted biopsy” for the national project “Bioptic Advanced Robotic Technologies in OncoLOgy – B.A.R.T.O.LO”. Since 2008 she is a Member of the IEEE Robotics and Automation Society, and a Senior Member since 2017.
Since 2018 she is in the Technology Committee of the European Association of Endoscopic Surgery (EAES). She is involved in the organization of international conferences and workshops. Currently she serves as Associate Editor of Journal of Intelligent Service Robotics (JIST) and she is on the editorial board of prestigious conferences in the field of robotics.

Massimilano Fraldi

Massimiliano Fraldi is associate professor of Mechanics of Solids and Structures, Tissue Mechanics and Micro-mechanics of Heterogeneous Materials at the Polytechnic School of the University of Napoli Federico II, Italy, where he is member of the Doctoral College of Structural and Geotechnical Engineering and Seismic Risk at the Department of Structures for Engineering and Architecture (DIST). He is also associate to the Interdisciplinary Research Center on Biomaterials (CRIB), a leading European Institution in the field of Biomaterials, to the Center for Structural Composites for Innovative Construction (SCIC) and is affiliated member of the Institute of applied Sciences and Intelligent Systems (ISASI) of the National Research Council of Italy. He is also fellow of the Italian Association of Theoretical and Applied Mechanics (AIMETA), the National Interuniversity Consortium for Material Science and Technology (INSTM) and member of the Society for Natural Philosophy (SNP, founded by Clifford Truesdell).

Costantino Menna

Costantino Menna is Assistant Professor at the University of Naples Federico II, where he graduated in Materials Engineering in 2009 and received his Ph.D. in Materials Engineering and Structures in 2013, working on damage modeling of advanced composite materials.
He is involved in several multidisciplinary research activities mainly focused on advanced materials for civil and industrial applications, including: finite element modeling of advanced composite materials, experimental and theoretical assessment of innovative materials used for structural retrofit of existing structures, and additive manufacturing in the construction industry. During his academic career, he has been visiting research scholar in several foreign institutions: École Polytechnique de Montréal (Canada), Department of Engineering Science and Mechanics of Penn State University (USA), Laboratoire de Mécanique des Solides of Ecole Polytechnique (Parigi), University of Greenwich (UK).
He is a member of several task groups of fib (Fédération Internationale du Béton) and member of RILEM Technical Committee: “Digital fabrication with cement-based materials”. He is a co-founder of the Spinoff FED, Future Environmental Design, providing services on the integration of Building Integration Modeling (BIM) and Sustainability in the construction sector.
He is author of more than 30 scientific papers published in international peer-reviewed journals and 3 national and international patents.

Paolo A. Netti

Paolo A. Netti received his PhD in Chemical Engineering in 1994 from the University of Naples Federico II. During his doctoral studies he has worked at the IRC in Biomedical Materials at the University of London and later for his post-doctoral stage joined Harvard University for more than 4 years. He is full professor of Biomaterials and Tissue Engineering at the University of Naples Federico II and he is the coordinator of the Center for Advanced Biomaterials for Health Care IIT@CRIB.
His research interests mainly focus on elucidating the complex interplays between materials properties and biological entities such as biomolecules, cells and tissues. His activities span from the basic understanding of the mechanisms governing cell’s recognition and response to material stimuli, to the technological development of novel class of biomaterials and devices able to control cell fate and functions. He participated to several European Scientific Commission panels for defining a viable European roadmap for the development of novel biomaterials platforms, he is a panel member of ERC advanced grant evaluation committee and has also served as scientific tutor of several research platforms from the Italian Minister of Research and University.

Rossana Pasquino

Rossana Pasquino, class 1982, received her master’s degree in Chemical Engineering cum laude in 2005 at Università degli Studi di Napoli Federico II (Unina).

In 2005, she started a Ph.D. at Unina on suspensions of hard spheres in viscoelastic solutions. Her Ph.D. program was part of a joint project between Unina and KU Leuven, in Belgium, where she performed half of her studies. She obtained the Ph.D. degree in 2008. After her Ph.D., she worked for one year as Postdoctoral researcher between Belgium and Italy, dealing with flow-induced microstructure in suspensions. After that, she won a Marie Curie fellowship (within the framework of the initial training network “Dynacop”) and she moved to Heraklion, in Crete, where she spent two years at FORTH-IESL, studying the dynamics of complex polymers.

Since 2012, she has been working as a permanent researcher at the Department of Chemical, Materials and Industrial Production Engineering (DICMaPI, Unina). In 2016, she became Associate Professor at the same department. She received the Italian habilitation to Ordinary Professor in 2018.

She teaches Rheology and Transport Phenomena and she is leading a Rheology group involving postdocs, PhDs and Master students. R. Pasquino’s work on rheology of complex fluids is globally acknowledged in the rheology community, especially concerning the use of rheology as a tool to detect morphology and microstructural properties of soft matter. Her studies focus on different aspects of the rheology of viscoelastic solutions, colloids and polymers.

In 2015, she was visiting professor at ETH Zurich, in Switzerland, where she worked on microfluidics of micellar solutions. In 2018, she visited Queen’s University in Kingston, Canada, to investigate polymer degradation through rheological tools.

She is the author of approximately 50 scientific works on peer-reviewed journals (h-index 16, number of citations>700) and she is involved in various national and international projects.

Since 2019, she is an Associate Editor of Physics of Fluids and she is part of the Editorial Board of Soft Matter.

She was in the Organization Committee of the Annual European Rheology Conference (AERC) in 2018, and chairman/invited keynote speaker in various international conferences.

She is the recipient of the Distinguished Young Rheologist Award 2018, given by TA Instruments.

Valentina Preziosi

Valentina Preziosi si è laureata in Ingegneria chimica nel 2007 con  una tesi  sperimentale sulla “Messa a punto di un sistema in vitro per lo studio della deformabilità dei globuli rossi in microcapillari” all’Università degli studi di Napoli Federico II ed ha conseguito il Dottorato di Ricerca in Biotecnologia Industriale nel 2012, discutendo una tesi sulla “Modellazione e sviluppo di reattori a topografia controllata e le loro applicazioni nel campo della biotecnologia industriale” in collaborazione con il centro di ricerca e sviluppo della Procter and Gamble a Bruxelles. Nel 2022 è diventata RtdA all’Università degli studi di Napoli Federico II.

Svolge attivitá didattica e di ricerca nell’ambito dello studio microstrutturale e dei fenomeni di trasporto di fluidi complessi, sia di interesse biologico che industriale, in sistemi microfluidici. L’integrazione di tali sistemi microfluidici con transistor organici per il sensing e monitoraggio di tali fluidi è oggetto principale di studio e pubblicato nella gran parte dei suoi articoli scientifici e nei progetti vinti.

È autore di 32 articoli su riviste internazionali peer-reviewed (~30% corresponding, ~30% primo nome, >80% Q1), circa 20 atti di convegni, 1 capitolo di libro e circa 40 partecipazioni a convegni. Il numero di citazioni è ~800, con H-index 13 (fonte: Scopus). 

Lei è/è stata Responsabile nazionale (Principal Investigator) nei seguenti progetti di ricerca:

-ISSNAF (Italian Scientists and Scholars of North America Foundation) – EasyDial inc – “Studio di fattibilità per l’utilizzo della tecnologia micro-fluidica per le operazioni di filtraggio ematico”.

STAR L1 2018 come Principal Investigator – “Biosensing through Immuno-microfluidics”. –FISR 2020 come Principal Investigator – “Rilevamento ed amplificazione della presenza di immunoglobuline in sangue affetto da COVID-19 con l’uso di biosensori”.

PRIN 2022 come Principal Investigator – “A lab-on-a-chip integrated with electrochemical transistors for cardiac biomarkers evaluation in human blood”.

Margherita Ruoppolo

Margherita Ruoppolo graduated in Chemistry in 1990 and got her PhD in Chemical Sciences in 1997 at the University of Naples “Federico II”. From 1993 to 1994 she carried out research at the Biological Laboratory of the University of Kent, Canterbury, United Kingdom.

She began her university career in 1996 as Researcher (SSD BIO-10 “Biochemistry”) at the University of Salerno. In 2001 she became Associate Professor (SSD BIO-10 “Biochemistry”) at the Faculty of Medicine of the University of Naples Federico II. Since 2007 she is Full Professor (SSD BIO-10 “Biochemistry”) at the Faculty of Medicine of the University of Naples Federico II. Since 2003 she has been responsible for the INTERDEPARTMENTAL PROGRAM: Development of innovative spectroscopic technologies for the screening and diagnosis of diseases of the Laboratory Medicine DAI, University Policlinico, University of Naples “Federico II”. Since 2018 she has been responsible for the laboratory of newborn screening at CEINGE.

She teaches Biochemistry courses at the School of Medicine of the University of Naples “Federico II” and she is in charge of the teaching of Proteomics (CdL Biotechnology of Health – University of Naples Federico II).

 From November 2011 to October 2016 she was President of the Council for the Degree Course in Audioprosthetic Techniques

The scientific activity of Margherita Ruoppolo has focused on the themes listed below:

-Characterization of post-translational modifications with particular regard to the dynamic characterization of disulphide bridges and to oxidative folding processes.

-Differential and functional proteomics methodologies in molecular medicine

-Metabolomics methodologies in the study of inborn errors of metabolism

– Definition of altered intracellular pathways in hereditary diseases of the intermediate metabolism.

Enza Torino

Enza Torino gained a Ph.D. in Chemical Engineering on the development of novel technologies for the production of nanoparticles for nanomedicine. Lifetime goal of her research interests has always been obtaining nanostructures and exploiting their fascinating properties using thermodynamics. She spent part of her Ph.D as at University of Texas at Austin – Texas (USA), to research emulsion and microemulsion formation for pharmaceutical products to study how nanoparticles can be modified using surfactants to enhance their delivery properties in a biological environment. After her Ph.D., she worked as Guest Scientist at the “School in Advanced Optical Technologies” (SAOT) established at the University of Erlangen-Nuremberg – Department of Chemical and Bioengineering, within the framework of the Excellence Initiative of the German Federal and State Governments. Here, she studied the mechanism involved in drug-polymer nanoprecipitation using on situ laser diagnostic technique and the manipulation of pharmaceutical emulsions to produce nanospheres or nanocapsules by Microfluidics. From 2010 to 2016, she worked as Post Doc Researcher at Fondazione Istituto Italiano di Tecnologia in the Theranostic Engineered Nanoshuttle (TeNs) Platform, where she designed novel polymer-based engineered nanostructures for in vivo application in diagnosis and therapy of several pathologies. She is currently working as a tenure-track researcher in Bioengineering at the University of Naples “Federico II” at the Department of Chemical, Materials and Production Engineering on the design of multimodal imaging nanoparticles for theranostics and she teaches “Diagnostic Devices and Drug Delivery” in the framework of the International Master Degree in Industrial Bioengineering. She is also leading 3 spin-off and start-up projects in Life Sciences based on patented technologies. Currently, Enza Torino is also involved as a Principal Investigator in several projects to develop theranostic systems for the nanobiotechnology field and in several national and international collaborations with industrial and academics partners.

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